(Associate) Director, Clinical Science

Centessa Pharmaceuticals • Boston, MA, US • published 2026-09-21 22:42:50.117321

Description

*Centessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company,* *is a clinical\-stage company developing orexin receptor 2 (OX2R) agonists as a new class of medicines for the treatment of narcolepsy and potentially other sleep\-wake disorders. Centessa’s lead investigational candidate – cleminorexton (formerly ORX750\) – is being developed for narcolepsy type 1, narcolepsy type 2, and idiopathic hypersomnia. Centessa's OX2R agonist portfolio includes additional clinical and preclinical\-stage assets with potential utility across a broader range of neurological, neurodegenerative, and neuropsychiatric conditions.* *Headquartered in Boston, Massachusetts, Centessa was recognized as a* ***Great Place to Work****® in 2026\.* **Description of Role** Centessa is seeking an (Associate) Director, Clinical Science to provide scientific and clinical leadership for the design, execution, and interpretation of early\-stage (Phase 1/2\) clinical trials for our Orexin\-targeted programs in neurodegeneration and neuropsychiatric indications. This individual will serve as a scientific leader and key cross\-functional partner to Clinical Development, Clinical Operations, Translation...

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