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Senior Bioinformatics Engineer, Infrastructure

Repertoire Immune Medicines • Watertown, MA, US • published 2026-10-28 03:17:06.905417

Description

Repertoire Immune Medicines is a clinical\-stage biotechnology company harnessing the power of the human immune system to develop transformative therapies for cancer and autoimmune disease. Using its proprietary DECODETM platform—which maps the immune synapse between T cell receptors (TCRs) and their antigen targets—Repertoire translates unique biological insights into potent and targeted off\-the shelf immune medicines. The company integrates deep protein engineering expertise with artificial intelligence, powered by a proprietary DECODE database of over one billion TCR\-antigen interactions, to accelerate discovery and optimize drug candidates. From its sites in Watertown, Massachusetts and Zurich, Switzerland, Repertoire is advancing a pipeline of T cell\-targeted immunotherapies with the potential to address a broad range of cancers and autoimmune disorders. The company’s lead oncology program, RPTR\-1\-201, a TCR bispecific, has initiated a Phase 1/2 clinical trial across multiple solid tumor indications. Repertoire plans to advance additional TCR bispecific therapies into clinical trials over the next 12\-18 months. In autoimmune disease, Repertoire is partnering with leading...

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